What are 5 types of teratogens?
Teratogenic agents include infectious agents (rubella, cytomegalovirus, varicella, herpes simplex, toxoplasma, syphilis, etc.); physical agents (ionizing agents, hyperthermia); maternal health factors (diabetes, maternal PKU); environmental chemicals (organic mercury compounds, polychlorinated biphenyl or PCB.
What are the 4 categories of teratogens?
Teratogens are classified into four types: physical agents, metabolic conditions, infection, and finally, drugs and chemicals.
What is the most common type of teratogen?
Alcohol: One of the most commonly used teratogens is alcohol, and because half of all pregnancies in the United States are unplanned, it is recommended that women of child-bearing age take great caution against drinking alcohol when not using birth control or when pregnant (CDC, 2005).
Is cigarette smoke a teratogen?
Because the teratogenic agent in cigarette smoke remains controversial, the present study on rat embryos in culture examined specifically whether nicotine can cause neural dysmorphology and, hence, act as a nervous system teratogen.
Is Thalidomide a teratogen?
Thalidomide is a potent teratogen that induces a range of birth defects, most commonly of the developing limbs.
When are teratogens most harmful?
Time of exposure: Teratogens are most harmful early in pregnancy, starting about 10 to 14 days after conception to about 8 weeks into pregnancy. Genetics: Sometimes, the pregnant person’s or the baby’s unique genetics protect them or make them more vulnerable to certain teratogens.
Is a virus a teratogen?
Many viruses can be transmitted to the fetus and cause infection and tissure damage. Five viruses are known to be teratogenic in humans: cytomegalovirus, rubella, herpes simplex, Venezuelan equine encephalitis, and varicella viruses.
Is German measles a teratogen?
Rubella was one of the first viruses classified as a teratogen, a classification that introduced the possibility that environmental agents such as viruses could cause birth defects during embryological and fetal development.
Why is alcohol a teratogen?
Both alcohol and its primary metabolite, acetaldehyde, are teratogenic. Exposure during pregnancy may lead to fetal alcohol syndrome (FAS), and this is said to occur in a substantial proportion of infants born to mothers who are chronic, heavy daily drinkers.
Is folic acid a teratogen?
Folate deficiency has a well-established teratogenic effect, leading to an increasing risk of neural tube defects. This paper highlights the most recent medical literature about folate deficiency, be it maternal or paternal.